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Tonia J. Buchholz
Graduate Student
Research Advisor: David Sherman
M.A., Biochemistry, University of Wisconsin-Madison
B.A., Biochemistry, Ohio Wesleyan University
Cohort: 2005-2006
E-mail: toniab@umich.edu
Publications
1. Kittendorf, J.D., Beck, B.J., Buchholz, T.J., Seufert,
W., and Sherman, D.H., "Interrogating the Molecular Basis for
Multiple Macrolactone Ring Formation by the Pikromycin Polyketide
Synthase", Chemistry and Biology, 2007, 14, 944.
2. Demo, S.D., Kirk, C.J., Aujay, M.A., Buchholz, T.J., Dajee,
M., Ho, M.N., Jiang, J., Laidig, G.J., Lewis, E.R., Parlati,
F., Shenk, K.D., Smyth, M.S., Sun, C.M., Vallone, M.K., Woo,
T.M., Molineaux, C.J. and Bennett, M.K., "Antitumor Activity
of PR-171, a Novel Irreversuble Inhibitor of the Proteasome",
Cancer Res., 2007, 67, 6383.
3. Grüschow, S., Buchholz, T.J., Seufert, W., Dordick,
J.S. and Sherman, D.H., "Substrate Profile Analysis and
ACP-Mediated Acyl Transfer in Streptomyces coelicolor Type
III Polyketide Synthases", ChemBioChem, 2007, 8, 863.
4. Bennett, M.K., Buchholz, T.J., Demo, S.D., Laidig, G.J.,
Lewis, E.R. and Smyth, M.S., "Compounds for Enzyme Inhibition",
U.S./International Patent Applications 2006/0088471 A1; WO
2006/045066 A2, April 27, 2006
5. Schuster, M.C., Mann, D.A., Buchholz, T.J., Johnson, K.M.,
Thomas, W.J. and Kiessling, L.L., "Parallel Synthesis
of Glycomimetic Libraries: Targeting the C-type Lectin Family",
Org. Lett., 2003, 5(9), 1407.
6. Buchholz, T. and Burke, T., "Methods and Kits for
Assays Utilizing Flourescence Polarization", U.S. Patent
Application 20030224469, December 4, 2003.
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