Faculty

Assistant Professor of Molecular and Integrative Physiology; Assistant Professor of Internal Medicine
Expertise: Cancer Chemical Biology
Research:
Tumor metabolism, cancer, pancreatic cancer, autoimmunity
  • Assistant Professor
Assistant Professor of Pharmacology, University of Michigan Medical School
Expertise: Macromolecular Structure and Function
Research:
GPCR structure and signaling
Research Professor, Life Sciences Institute; Associate Dean for Academic Programs and Initiatives, U-M Rackham Graduate School; Edwin Vedejs Collegiate Professor of Chemistry
Expertise: Cancer Chemical Biology
Research:
Discovery of artificial transcriptional regulators
Professor of Chemistry; Professor of Biological Chemistry
Expertise: Chemical Microbiology, Macromolecular Structure and Function
Research:
Enzyme mechanism and structure, protein design
Arthur F. Thurnau, Margaret and Herman Sokol Professor in Medicinal or Synthetic Chemistry; Arthur F. Thurnau Professor of Chemistry
Expertise: Macromolecular Structure and Function
Research:
Synthetic Chemistry and Glycoscience
  • Research Assistant Professor, Life Sciences Institute Assistant Professor, Cell and Developmental Biology Assistant Professor, Biological Chemistry
Associate Professor of Chemistry
Expertise: Cancer Chemical Biology, Macromolecular Structure and Function
Research:
Natural products with anticancer activity, synthesis, medicinal chemistry, cardiotonic steroids
Associate Professor of Molecular, Cellular, and Developmental Biology
Expertise: Cancer Chemical Biology, Macromolecular Structure and Function
Research:
Telomerase, telomeres, cancer, aging biochemistry
Research Associate Professor, Life Sciences Institute; Associate Professor of Chemistry
Expertise: Chemical Microbiology
Research:
Development of biocatalytic methods, complex molecule synthesis, natural products
  • Director of Molecular and Cellular Pathology Graduate Program, Medical School
Associate Professor of Pathology
Expertise: Cancer Chemical Biology
Research:
Discovery, design and development of small molecules as new molecularly targeted therapies for cancer
  • Associate Chair of Biological Chemistry
Associate Professor of Biological Chemistry
Expertise: Cancer Chemical Biology, Macromolecular Structure and Function
Research:
Protein/nucleic acid interactions and DNA repair
Rowena G. Matthews Collegiate Professor in the Life Sciences; Professor of Cell and Developmental Biology
Expertise: Macromolecular Structure and Function
Research:
Using single particle cryo-electron microscopy (cryo-EM) in combination with biophysical, biochemical, and genetic approaches to structurally and functionally characterize biologically important but structurally challenging molecular machines.
Associate Professor of Cell & Developmental Biology
Expertise: Cancer Chemical Biology
Research:
Mitosis, Cytokinesis, Microtubule, Kinesin, Microscopy, Reconstitution
Warner-Lambert/Parke-Davis Professor in Medicine; Professor of Pharmacology; Associate Chair, Innovation
Expertise: Chemical Neurobiology, Macromolecular Structure and Function
Research:
Protein folding diseases; Hsp90, Hsp70; molecular chaperones; nitric oxide synthase; ubiquitination and protein quality control; reactive metabolites and mass spectrometry.
  • Associate Director of the Program in Chemical Biology
Associate Professor of Biological Chemistry
Expertise: Macromolecular Structure and Function
Research:
We investigate the reaction mechanisms of flavin-dependent enzymes, especially the reactions of O2 and the formation of novel intermediates, using kinetic, spectroscopy, and anything else that helps. Flavoenzymes are constantly being discovered in all areas of biology, making them inviting drug targets, models for detailed studies of structure-function relationships and enzyme evolution. And surprisingly, despite decades of intense enzymology, novel intermediates continue to be discovered

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