Faculty

Assistant Professor of Chemistry; Assistant Professor of Biophysics
Expertise: Macromolecular Structure and Function
Research:
Examining how biomolecular structure contributes to the processing pathways of two classes of molecules essential for human health: mitochondrial RNAs ((mt)RNAs) and vitamin B12.
Seyhan N. Ege Assistant Professor of Chemistry
Expertise: Macromolecular Structure and Function
Research:
Cells employ a vast arsenal of tactics to control gene expression - including chemically modifying biomolecules to regulate their biogenesis, function, and stability. In the Koutmou lab we study the post-transcriptional modification of messenger RNAs (mRNAs). The prevalence and significance of mRNA modification is rapidly being recognized; perturbations in mRNA modification are now linked to diseases including obesity, cancers and diabetes. The goal of our work is to understand how enzymatic mRN
Associate Professor of Molecular and Integrative Physiology; Associate Professor of Internal Medicine
Expertise: Cancer Chemical Biology
Research:
Tumor metabolism, cancer, pancreatic cancer, autoimmunity
Assistant Professor of Pharmacology, University of Michigan Medical School
Expertise: Macromolecular Structure and Function
Research:
GPCR structure and signaling
Research Professor, Life Sciences Institute; Associate Dean for Academic Programs and Initiatives, U-M Rackham Graduate School; Edwin Vedejs Collegiate Professor of Chemistry
Expertise: Cancer Chemical Biology
Research:
Discovery of artificial transcriptional regulators
Professor of Chemistry; Professor of Biological Chemistry
Expertise: Chemical Microbiology, Macromolecular Structure and Function
Research:
Enzyme mechanism and structure, protein design
Arthur F. Thurnau, Margaret and Herman Sokol Professor in Medicinal or Synthetic Chemistry; Arthur F. Thurnau Professor of Chemistry
Expertise: Macromolecular Structure and Function
Research:
Synthetic Chemistry and Glycoscience
  • Research Assistant Professor, Life Sciences Institute Assistant Professor, Cell and Developmental Biology Assistant Professor, Biological Chemistry
Professor of Chemistry
Expertise: Cancer Chemical Biology, Macromolecular Structure and Function
Research:
Natural products with anticancer activity, synthesis, medicinal chemistry, cardiotonic steroids
Associate Professor of Molecular, Cellular, and Developmental Biology
Expertise: Cancer Chemical Biology, Macromolecular Structure and Function
Research:
Telomerase, telomeres, cancer, aging biochemistry
  • Assistant Professor
  • Faculty scholar, Center for RNA Biomedicine
  • Member, Rogel Cancer Center
Biological Chemistry
Expertise: Cancer Chemical Biology
Research:
We study mRNA regulatory features that control protein output
  • Director of Molecular and Cellular Pathology Graduate Program, Medical School
Professor of Pathology
Expertise: Cancer Chemical Biology
Research:
Discovery, design and development of small molecules as new molecularly targeted therapies for cancer
  • Associate Chair of Biological Chemistry
Professor of Biological Chemistry
Expertise: Cancer Chemical Biology, Macromolecular Structure and Function
Research:
Protein/nucleic acid interactions and DNA repair
  • Assistant Professor, Microbiology and Immunology
Microbiology and Immunology
Expertise: Macromolecular Structure and Function
Research:
Functional genomics in fungal pathogens
  • Rowena G. Matthews Collegiate Professor in the Life Sciences
Professor of Cell and Developmental Biology
Expertise: Macromolecular Structure and Function
Research:
Using single particle cryo-electron microscopy (cryo-EM) in combination with biophysical, biochemical, and genetic approaches to structurally and functionally characterize biologically important but structurally challenging molecular machines.

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